MULTI-SCALE MODELING AND COMPUTATIONAL SURGERY: APPLICATION TO BREAST CONSERVATIVE THERAPY
M. Garbey, D. Thanoon, R.Salmon, B. Bass UDC: (618.19-089:519.87)
Abstract:
After a lumpectomy, cosmetic defect occurs up to 30% of the time and have negative impact on the quality of life of the patient Clough et al. [1998], Veiga et al. [2010]. The complex interplay between mechanical forces due to gravity, the breast tissue distribution, and the internal stress generated by the healing process play dominant roles in determining the success or failure of the surgery. The purpose of this project is to develop a mathematical model for assessing and predicting the effect of lumpectomies on postsurgical cosmesis - see M.Garbey et al. [2010] chapter 1 and 15. We will present an image based domain decomposition method coupling the mechanical model of the breast tissue with a model simulating the slow healing process.
