TRANSPORT AND BIOMECHANICAL STUDIES IN THE ISOLATED BLOOD VESSEL SEGMENT
M. Rosic, S. Pantovic, M. Colic, V. Ilic, Z. Tepic. UDC: (612.13/.15)
Experiments on the isolated blood vessels are very important for investigation of drug effects, new drug development, blood vessels regulatory mechanisms and other functional and biomechanical investigations. In this paper we designed an experimental study and mathematical model for dynamics response of blood vessel under different load conditions. The results from these experiments demonstrated influence of shear stress dynamics and other biomechanical properties of the blood vessel. Also the effects of drugs are different even they produce the same relaxation or constriction at alternate steady states. Experimental data for different shear stress-strain curves were fitted using exponential mathematical function. This research is very important for biomechanical analysis of blood vessels during dynamics loads.