MODELING OF CELL MECHANICAL RESPONSE BY BIPHASIC MODELS WITH ACTIVATION

A biphasic model of cell is presented in the paper. The model consists of the solid and fluid phases with deformation of solid and fluid flow through pores. Relative motion between the solid and fluid governed by Darcy’s law. Activation corresponding to the biochemical processes which transform biochemical energy into the mechanical action is included into the model through the active stresses in the selected fiber directions. The activation evolution is specified by a time function. Solved examples demonstrate applicability of the proposed cell model.